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Old blood stem cells feel the stress


Ageing is accompanied by deterioration in the haematopoietic stem cells that are responsible for regenerating the blood system. Cellular stress in the aged stem cells could be a cause of this decline. See Letter p.198

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Figure 1: Replication stress in ageing cells.


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Correspondence to Jiri Bartek or Zdenek Hodny.

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Bartek, J., Hodny, Z. Old blood stem cells feel the stress. Nature 512, 140–141 (2014).

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