Extended Data Figure 2 : The ToothMaker modelling interface and morphodynamic model of tooth development.

From: Replaying evolutionary transitions from the dental fossil record

Extended Data Figure 2

The model parameters can be changed manually or scanned automatically (Options-menu). For descriptions of parameters, see Methods. The figures illustrate the growth factor concentration (secreted from the enamel knots) showing the future cusp areas. Initial activator concentration (Ina) is not used in the model. The model can be downloaded at (http://www.biocenter.helsinki.fi/bi/evodevo/toothmaker.html).