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Structural biology

Wobble puts RNA on target

Enzymes that attach amino acids to transfer RNAs during protein synthesis must recognize both substrates specifically. Crystal structures reveal a mechanism that explains the RNA specificity for one such system. See Article p.507

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Figure 1: Conformational effects of a single base pair in a transfer RNA.

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Correspondence to Karin Musier-Forsyth.

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Vargas-Rodriguez, O., Musier-Forsyth, K. Wobble puts RNA on target. Nature 510, 480–481 (2014). https://doi.org/10.1038/nature13502

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