Extended Data Figure 1 : PikAIII sample preparation and raw EM images.

From: Structure of a modular polyketide synthase

Extended Data Figure 1

a, SDS–polyacrylamide gel electrophoresis (SDS–PAGE) gel of each purified form of PikAIII examined by cryo-EM. The numbers on the left indicate molecular weight in kDa. b, Raw EM image of holo-PikAIII particles embedded in negative stain. c, Raw cryo-EM image of holo-PikAIII particles. d, Boxed-out particle projections of holo-PikAIII.