Extended Data Figure 1 : A schematic of the analysis protocol.

From: Neuropsychosocial profiles of current and future adolescent alcohol misusers

Extended Data Figure 1

A schematic of the analysis protocol showing the inner cross-validation loop (to optimize the imaging parameters), the middle cross-validation loop (to optimize the elastic net parameters) and the outer loop (to quantify the generalizability). An external validation was also performed to quantify generalizability to a slightly different phenotype. The percentage of the sample used in each step is also displayed. AUC, area under the receiver-operating characteristic curve.