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Cancer biology

Enzyme meets a surprise target

An enzyme previously implicated in gene regulation has now been found to have a role in cancer progression, potentiating an intracellular signalling pathway that is driven by a mutated K-Ras protein. See Letter p.283

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Figure 1: SMYD3 potentiates signalling in K-Ras-driven cancer.


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Correspondence to Martin McMahon.

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Deuker, M., McMahon, M. Enzyme meets a surprise target. Nature 510, 225–226 (2014).

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