Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Reproductive biology

Sperm protein finds its mate

Knowledge of the sperm-specific protein that is required for the attachment of sperm to eggs during fertilization in mammals has led to the identification of the protein's receptor on the egg's plasma membrane. See Article p.483

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: An adhesion complex mediates binding of sperm to eggs.

References

  1. Bianchi, E., Doe, B., Goulding, D. & Wright, G. J. Nature 508, 483–487 (2014).

    Article  ADS  CAS  Google Scholar 

  2. Inoue, N., Ikawa, M., Isotani, A. & Okabe, M. Nature 434, 234–238 (2005).

    Article  ADS  CAS  Google Scholar 

  3. Ellerman, D. A. et al. Mol. Reprod. Dev. 76, 1188–1199 (2009).

    Article  CAS  Google Scholar 

  4. Wright, G. J. Mol. Biosyst. 5, 1405–1412 (2009).

    Article  CAS  Google Scholar 

  5. Chen, C. et al. Nature 500, 486–489 (2013).

    Article  ADS  CAS  Google Scholar 

  6. Wibowo, A. S. et al. Proc. Natl Acad. Sci. USA 110, 15180–15188 (2013).

    Article  ADS  CAS  Google Scholar 

  7. Inoue, N. et al. Development 140, 3221–3229 (2013).

    Article  CAS  Google Scholar 

  8. Podbilewicz, B. et al. Dev. Cell 11, 471–481 (2006).

    Article  CAS  Google Scholar 

  9. Millay, D. P. et al. Nature 499, 301–305 (2013).

    Article  ADS  CAS  Google Scholar 

  10. Jégou, A. et al. Proc. Natl Acad. Sci. USA 108, 10946–10951 (2011).

    Article  ADS  Google Scholar 

  11. Gardner, A. J. & Evans, J. P. Reprod. Fertil. Dev. 18, 53–61 (2006).

    Article  CAS  Google Scholar 

  12. Wortzman-Show, G. B., Kurokawa, M., Fissore, R. A. & Evans, J. P. Mol. Hum. Reprod. 13, 557–565 (2007).

    Article  CAS  Google Scholar 

  13. Wang, M., Lv, Z., Shi, J., Hu, Y. & Xu, C. Mol. Reprod. Dev. 76, 794–801 (2009).

    Article  CAS  Google Scholar 

  14. Wassarman, P. M. & Litscher, E. S. Methods Mol. Biol. 475, 99–113 (2008).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Paul M. Wassarman.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wassarman, P. Sperm protein finds its mate. Nature 508, 466–467 (2014). https://doi.org/10.1038/nature13227

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature13227

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing