Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Bone biology

Vessels of rejuvenation

The identification of specialized endothelial-cell populations in the blood vessels of bones, and their signalling pathways, reveals how the vasculature contributes to bone formation. See Article p.323 & Letter p.376

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Type H endothelial cells couple angiogenesis to osteogenesis.

References

  1. Potente, M., Gerhardt, H. & Carmeliet, P. Cell 146, 873–887 (2011).

    CAS  Article  Google Scholar 

  2. Ding, B. S. et al. Nature 505, 97–102 (2014).

    ADS  Article  Google Scholar 

  3. Hu, J. et al. Science 343, 416–419 (2014).

    ADS  CAS  Article  Google Scholar 

  4. Kusumbe, A. P., Ramasamy, S. K. & Adams, R. H. Nature 507, 323–328 (2014).

    ADS  CAS  Article  Google Scholar 

  5. Ramasamy, S. K., Kusumbe, A. P., Wang, L. & Adams, R. H. Nature 507, 376–380 (2014).

    ADS  CAS  Article  Google Scholar 

  6. Pugh, C. W. & Ratcliffe, P. J. Nature Med. 9, 677–684 (2003).

    CAS  Article  Google Scholar 

  7. Thomas, J. L. et al. Cell Mol. Life Sci. 70, 1779–1792 (2013).

    CAS  Article  Google Scholar 

  8. Wong, B. W., Kuchnio, A., Bruning, U. & Carmeliet, P. Trends Biochem. Sci. 38, 3–11 (2013).

    CAS  Article  Google Scholar 

  9. Wan, C. et al. Proc. Natl Acad. Sci. USA 105, 686–691 (2008).

    ADS  CAS  Article  Google Scholar 

  10. Whitaker, M., Guo, J., Kehoe, T. & Benson, G. N. Engl. J. Med. 366, 2048–2051 (2012).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ferdinand le Noble.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

le Noble, F., le Noble, J. Vessels of rejuvenation. Nature 507, 313–314 (2014). https://doi.org/10.1038/nature13210

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature13210

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing