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Cancer

Tumours outside the mutation box

Analyses of ependymoma brain tumours reveal a gene rearrangement in one subtype, but no DNA mutations in two others, suggesting that mechanisms for cancer initiation are broader than is typically thought. See Articles p.445 & p.451

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Figure 1: Genomic characterization of ependymomas.

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Correspondence to Rogier Versteeg.

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Versteeg, R. Tumours outside the mutation box. Nature 506, 438–439 (2014). https://doi.org/10.1038/nature13061

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