Wnt signalling molecules are thought to direct the development of an organism by spreading through tissues. But flies grow with almost normal appendages even when their main Wnt protein cannot move. Two scientists discuss the implications of this finding for our understanding of development. See Article p.180
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References
Alexandre, C., Baena-Lopez, A. & Vincent, J.-P. Nature 505, 180–185 (2014).
Lawrence, P. A. & Struhl, G. Cell 85, 951–961 (1996).
Zecca, M., Basler, K. & Struhl, G. Cell 87, 833–844 (1996).
Nellen, D., Burke, R., Struhl, G. & Basler, K. Cell 85, 357–368 (1996).
Baena-Lopez, L. A., Alexandre, C., Mitchell, A., Pasakarnis, L. & Vincent, J.-P. Development 140, 4818–4825 (2013).
Zecca, M. & Struhl, G. Development 134, 3001–3010 (2007).
MacDonald, B. T., Tamai, K. & He, X. Dev. Cell 17, 9–26 (2009).
Neumann, C. J. & Cohen, S. M. Development 124, 871–880 (1997).
Locke, M. & Huie, P. Tissue Cell 13, 787–803 (1981).
Gradilla, A.-C. & Guerrero, I. Curr. Opin. Genet. Dev. 23, 363–373 (2013).
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Morata, G., Struhl, G. Tethered wings. Nature 505, 162–163 (2014). https://doi.org/10.1038/nature12848
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DOI: https://doi.org/10.1038/nature12848