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Antibiotics

Killing the survivors

Antibiotic-tolerant, dormant variants of otherwise antibiotic-sensitive bacteria underlie many chronic and relapsing infections. A small molecule has been identified that can efficiently eradicate these persister cells. See Article p.365

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Figure 1: ADEPs activate ClpP and kill persister bacteria.

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Correspondence to Kenn Gerdes or Hanne Ingmer.

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Gerdes, K., Ingmer, H. Killing the survivors. Nature 503, 347–349 (2013). https://doi.org/10.1038/nature12834

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