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Structural biology

Pivotal findings for a transcription machine

Nature volume 502, pages 629–630 (2013)Cite this article

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Crystal structures of the complete RNA polymerase I complex are now revealed. The structures link the opening and closing of this enzyme's DNA-binding cleft to the control of transcription. See Articles p.644 & p.650

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Figure 1: Structure of RNA polymerase I.

Notes

  1. *This article and the papers under discussion2,3 were published online on 23 October 2013.

References

  1. Russell, J. & Zomerdijk, J. C. B. M. Trends Biochem. Sci. 30, 87–96 (2005).

    Article  CAS  Google Scholar 

  2. Fernández-Tornero, C. et al. Nature 502, 644–649 (2013).

    Article  ADS  Google Scholar 

  3. Engel, C., Sainsbury, S., Cheung, A. C., Kostrewa, D. & Cramer, P. Nature 502, 650–655 (2013).

    Article  ADS  CAS  Google Scholar 

  4. Werner, F. & Grohmann, D. Nature Rev. Microbiol. 9, 85–98 (2011).

    Article  CAS  Google Scholar 

  5. Cramer, P. et al. Annu. Rev. Biophys. 37, 337–352 (2008).

    Article  CAS  Google Scholar 

  6. Vannini, A. & Cramer, P. Mol. Cell 45, 439–446 (2012).

    Article  CAS  Google Scholar 

  7. Kuhn, C.-D. et al. Cell 131, 1260–1272 (2007).

    Article  CAS  Google Scholar 

  8. Geiger, S. R. et al. Mol. Cell 39, 583–594 (2010).

    Article  CAS  Google Scholar 

  9. Armache, K.-J., Kettenberger, H. & Cramer, P. Proc. Natl Acad. Sci. USA 100, 6964–6968 (2003).

    Google Scholar 

  10. Bushnell, D. A. & Kornberg, R. D. Proc. Natl Acad. Sci. USA 100, 6969–6973 (2003).

    Article  ADS  CAS  Google Scholar 

  11. Tagami, S. et al. Nature 468, 978–982 (2010).

    Article  ADS  CAS  Google Scholar 

  12. Weixlbaumer, A., Leon, K., Landick, R. & Darst, S. A. Cell 152, 431–441 (2013).

    Article  CAS  Google Scholar 

  13. Blattner, C. et al. Genes Dev. 25, 2093–2105 (2011).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Joost Zomerdijk is at the Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.,

    Joost Zomerdijk

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  1. Joost Zomerdijk
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Correspondence to Joost Zomerdijk.

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Zomerdijk, J. Pivotal findings for a transcription machine. Nature 502, 629–630 (2013). https://doi.org/10.1038/nature12700

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