A drug already used to treat Parkinson's disease induces repair of the damage that occurs to the myelin sheath around nerve fibres during multiple sclerosis. The finding offers new therapeutic avenues for this disease. See Article p.327
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
*This article and the paper under discussion2 were published online on 9 October 2013.
Hauser, S. L., Chan, J. R. & Oksenberg, J. R. Ann. Neurol. 74, 317–327 (2013).
Deshmukh, V. et al. Nature 502, 327–332 (2013).
Burgyone, K., Aduri, K., Ananth, J. & Parameswaran, S. Curr. Pharm. Des. 10, 2239–2248 (2004).
De Angelis, F., Bernardo, A., Magnaghi, V., Minghetti, L. & Tata, A. M. Dev. Neurobiol. 72, 713–728 (2012).
Gold, R., Linington, C. & Lassmann, H. Brain 129, 1953–1971 (2006).
Ludwin, S. K. Lab. Invest. 43, 382–387 (1980).
Franklin, R. J. M. & Ffrench-Constant, C. Nature Rev. Neurosci. 9, 839–855 (2008).
Patrikios, P. et al. Brain 129, 3165–3172 (2006).
Chang, A., Tourtellotte, W. W., Rudick, R. & Trapp, B. D. N. Engl. J. Med. 346, 165–173 (2002).
Jacobs, L. & Johnson, K. P. Arch. Neurol. 51, 1245–1252 (1994).
Steinman, L. Science 305, 212–216 (2004).
Nicholas, R., Young, C. & Friede, T. Expert Opin. Drug Safety 9, 905–915 (2010).
van der Walt, A. et al. Pharmacol. Ther. 126, 82–93 (2010).
About this article
Cite this article
Wekerle, H., Meinl, E. An old drug plays a new trick. Nature 502, 314–315 (2013). https://doi.org/10.1038/nature12694