Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Multiple sclerosis

An old drug plays a new trick

Nature volume 502, pages 314–315 (2013)Cite this article

Subjects

A drug already used to treat Parkinson's disease induces repair of the damage that occurs to the myelin sheath around nerve fibres during multiple sclerosis. The finding offers new therapeutic avenues for this disease. See Article p.327

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Identification of a myelin-promoting drug.

Notes

  1. *This article and the paper under discussion2 were published online on 9 October 2013.

References

  1. Hauser, S. L., Chan, J. R. & Oksenberg, J. R. Ann. Neurol. 74, 317–327 (2013).

    Article  CAS  Google Scholar 

  2. Deshmukh, V. et al. Nature 502, 327–332 (2013).

    Article  ADS  CAS  Google Scholar 

  3. Burgyone, K., Aduri, K., Ananth, J. & Parameswaran, S. Curr. Pharm. Des. 10, 2239–2248 (2004).

    Article  CAS  Google Scholar 

  4. De Angelis, F., Bernardo, A., Magnaghi, V., Minghetti, L. & Tata, A. M. Dev. Neurobiol. 72, 713–728 (2012).

    Article  CAS  Google Scholar 

  5. Gold, R., Linington, C. & Lassmann, H. Brain 129, 1953–1971 (2006).

    Article  Google Scholar 

  6. Ludwin, S. K. Lab. Invest. 43, 382–387 (1980).

    CAS  PubMed  Google Scholar 

  7. Franklin, R. J. M. & Ffrench-Constant, C. Nature Rev. Neurosci. 9, 839–855 (2008).

    Article  CAS  Google Scholar 

  8. Patrikios, P. et al. Brain 129, 3165–3172 (2006).

    Article  Google Scholar 

  9. Chang, A., Tourtellotte, W. W., Rudick, R. & Trapp, B. D. N. Engl. J. Med. 346, 165–173 (2002).

    Article  Google Scholar 

  10. Jacobs, L. & Johnson, K. P. Arch. Neurol. 51, 1245–1252 (1994).

    Article  CAS  Google Scholar 

  11. Steinman, L. Science 305, 212–216 (2004).

    Article  ADS  CAS  Google Scholar 

  12. Nicholas, R., Young, C. & Friede, T. Expert Opin. Drug Safety 9, 905–915 (2010).

    Article  Google Scholar 

  13. van der Walt, A. et al. Pharmacol. Ther. 126, 82–93 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Hartmut Wekerle is in the Hertie Senior Professor Group, Max Planck Institute of Neurobiology, 82152 Martinsried, Germany.,

    Hartmut Wekerle

  2. Edgar Meinl is at the Institute of Clinical Neuroimmunology, LMU Munich, 81377 Munich, Germany.,

    Edgar Meinl

Authors
  1. Hartmut Wekerle
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Edgar Meinl
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hartmut Wekerle.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wekerle, H., Meinl, E. An old drug plays a new trick. Nature 502, 314–315 (2013). https://doi.org/10.1038/nature12694

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12694

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research