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Immunology

B-cell development in the gut

Nature volume 501, pages 4243 (05 September 2013) | Download Citation

B cells arise in the bone marrow and go on to produce antibodies that protect against microbial infection. Surprisingly, it seems that B-cell development also occurs in the gut, where it is stimulated by resident microbes. See Letter p.112

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Affiliations

  1. Mark Schlissel is in the Departments of Molecular Biology, Cell Biology, and Biochemistry and Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island 02912, USA.

    • Mark Schlissel

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Correspondence to Mark Schlissel.

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DOI

https://doi.org/10.1038/nature12551

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