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Biological techniques

An embryonic view of tumour development

A genome-wide screen of developing mouse embryos, performed using RNA-interference techniques, finds new suspects in skin cancer. But some factors seem to have opposing roles in cancer and normal-tissue maintenance. See Article p.185

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Figure 1: Role of β-catenin in normal and cancer-prone skin cells.


  1. *This article and the paper under discussion1 were published online on 14 August 2013.


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Correspondence to Kim B. Jensen.

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Schweiger, P., Jensen, K. An embryonic view of tumour development. Nature 501, 171–172 (2013).

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