Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Structural biology

RNA exerts self-control

A crystal structure of two bound RNA molecules not only provides insight into how regulatory riboswitch sequences affect messenger RNA expression, but also expands our understanding of RNA structure and architecture. See Letter p.363

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: RNA meets RNA.

Notes

  1. *This article and the paper under discussion3 were published online on 28 July 2013.

References

  1. Atkins, J. F., Gesteland, R. F. & Cech, T. RNA Worlds (Cold Spring Harbor Laboratory Press, 2011).

    Google Scholar 

  2. Serganov, A. & Nudler, E. Cell 152, 17–24 (2013).

    Article  CAS  Google Scholar 

  3. Zhang, J. & Ferré-D'Amaré, A. Nature 500, 363–366 (2013).

    Article  ADS  CAS  Google Scholar 

  4. Green, N. J., Grundy, F. J. & Henkin, T. M. FEBS Lett. 584, 318–324 (2010).

    Article  CAS  Google Scholar 

  5. Yousef, M. R., Grundy, F. J. & Henkin, T. M. J. Mol. Biol. 349, 273–287 (2005).

    Article  CAS  Google Scholar 

  6. Lehmann, J., Jossinet, F. & Gautheret, D. Nucleic Acids Res. 41, 5494–5502 (2013).

    Article  CAS  Google Scholar 

  7. Grigg, J. C. et al. Proc. Natl Acad. Sci. USA 110, 7240–7245 (2013).

    Article  ADS  CAS  Google Scholar 

  8. Reiter, N. J. et al. Nature 468, 784–789 (2010).

    Article  ADS  CAS  Google Scholar 

  9. Korostelev, A., Trakhanov, S., Laurberg, M. & Noller, H. F. Cell 126, 1065–1077 (2006).

    Article  CAS  Google Scholar 

  10. Selmer, M. et al. Science 313, 1935–1942 (2006).

    Article  ADS  CAS  Google Scholar 

  11. Dethoff, E. A., Petzold, K., Chugh, J., Casiano-Negroni, A. & Al-Hashimi, H. M. Nature 491, 724–728 (2012).

    Article  ADS  CAS  Google Scholar 

  12. Winkler, W. C., Grundy, F. J., Murphy, B. A. & Henkin, T. M. RNA 7, 1165–1172 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alfonso Mondragón.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chetnani, B., Mondragón, A. RNA exerts self-control. Nature 500, 279–280 (2013). https://doi.org/10.1038/nature12460

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12460

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing