GIRK channels allow potassium ions to cross the cell membrane, thereby affecting the electrical status of the cell and so its functioning. Structural data now provide insight into the channels' mode of operation. See Article p.190
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*This article and the paper under discussion2 were published online on 5 June 2013.
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Reuveny, E. Ion channel twists to open. Nature 498, 182–183 (2013). https://doi.org/10.1038/nature12255