Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Structural biology

Ion channel twists to open

GIRK channels allow potassium ions to cross the cell membrane, thereby affecting the electrical status of the cell and so its functioning. Structural data now provide insight into the channels' mode of operation. See Article p.190

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The GIRK2 channel in action2.

Notes

  1. *This article and the paper under discussion2 were published online on 5 June 2013.

References

  1. Hibino, H. et al. Physiol. Rev. 90, 291–366 (2010).

    Article  CAS  Google Scholar 

  2. Whorton, M. R. & MacKinnon, R. Nature 498, 190–197 (2013).

    Article  ADS  CAS  Google Scholar 

  3. Logothetis, D. E., Kurachi, Y., Galper, J., Neer, E. J. & Clapham, D. E. Nature 325, 321–326 (1987).

    Article  ADS  CAS  Google Scholar 

  4. Wickman, K. D. et al. Nature 368, 255–257 (1994).

    Article  ADS  CAS  Google Scholar 

  5. Reuveny, E. et al. Nature 370, 143–146 (1994).

    Article  ADS  CAS  Google Scholar 

  6. Lüscher, C. & Slesinger, P. A. Nature Rev. Neurosci. 11, 301–315 (2010).

    Article  Google Scholar 

  7. Rubinstein, M. et al. J. Physiol. (Lond.) 587, 3473–3491 (2009).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Eitan Reuveny.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Reuveny, E. Ion channel twists to open. Nature 498, 182–183 (2013). https://doi.org/10.1038/nature12255

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12255

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing