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Cancer

Drug for an 'undruggable' protein

Scientists have long aimed to develop drugs against the cancer-associated protein KRAS, but without success. An approach that targets the oncoprotein's cellular localization reignites lost enthusiasm. See Letter p.638

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Notes

  1. 1.

    *This article and the paper under discussion2 were published online on 22 May 2013.

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Correspondence to Channing J. Der.

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Competing interests

C.J.D. has received honoraria from Bristol-Myers Squibb, Eli Lilly and Merck, and has a research contract with GlaxoSmithKline.

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Baker, N., Der, C. Drug for an 'undruggable' protein. Nature 497, 577–578 (2013). https://doi.org/10.1038/nature12248

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