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Inflammation links ageing to the brain

Inflammation-activated signalling pathways in the brain's hypothalamus control the production of ageing-related hormones. This finding provides a link between inflammation, stress responses and systemic ageing. See Article p.211

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Figure 1: Hypothalamic inflammation and control of systemic ageing.


  1. *This article and the paper under discussion were published online on 1 May 2013.


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Correspondence to Dana Gabuzda or Bruce A. Yankner.

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Gabuzda, D., Yankner, B. Inflammation links ageing to the brain. Nature 497, 197–198 (2013).

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