Arrestin proteins regulate cellular signalling cascades initiated by ubiquitous G-protein-coupled receptors. Crystal structures reveal that two arrestins undergo similar structural changes on activation. See Letters p.137 & p.142
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Borshchevskiy, V., Büldt, G. Active arrestin proteins crystallized. Nature 497, 45–46 (2013). https://doi.org/10.1038/nature12096
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