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Developmental biology

Segmentation within scale

Nature volume 493, pages 32–33 (2013)Cite this article

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Irrespective of an organism's size, the proportional sizes of its parts remain constant. An experimental model reveals size-dependent adjustment of segment formation and gene-expression oscillations in vertebrates. See Letter p.101

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Figure 1: Oscillating waves of gene expression in culture.

Notes

  1. *This article and the paper under discussion1 were published online on 19 December 2012.

References

  1. Lauschke, V. M., Tsiairis, C. D., François, P. & Aulehla, A. Nature 493, 101–105 (2013).

    Article  ADS  Google Scholar 

  2. Pourquié, O . Cell 145, 650–663 (2011).

    Article  Google Scholar 

  3. Oates, A. C., Morelli, L. G. & Ares, S. Development 139, 625–639 (2012).

    Article  CAS  Google Scholar 

  4. Saga, Y. Curr. Opin. Genet. Dev. 22, 331–338 (2012).

    Article  CAS  Google Scholar 

  5. Cooke, J. Nature 254, 196–199 (1975).

    Article  ADS  CAS  Google Scholar 

  6. Cooke, J. Nature 290, 775–778 (1981).

    Article  ADS  CAS  Google Scholar 

  7. Cooke, J. & Zeeman, E. C. J. Theor. Biol. 58, 455–476 (1976).

    Article  CAS  Google Scholar 

  8. Meinhardt, H. Models of Biological Pattern Formation (Academic, 1982).

    Google Scholar 

  9. Delaune, E. A., François, P., Shih, N. P. & Amacher, S. L. Dev. Cell 23, 995–1005 (2012).

    Article  CAS  Google Scholar 

  10. Soroldoni, D. & Oates, A. C. Curr. Opin. Genet. Dev. 21, 600–605 (2011).

    Article  CAS  Google Scholar 

  11. Ben-Zvi, D., Pyrowolakis, G., Barkai, N. & Shilo, B.-Z. Curr. Biol. 21, 1391–1396 (2011).

    Article  CAS  Google Scholar 

  12. Ben-Zvi, D. & Barkai, N. Proc. Natl Acad. Sci. USA 107, 6924–6929 (2010).

    Article  ADS  CAS  Google Scholar 

  13. Gregor, T., Bialek, W., de Ruyter van Steveninck, R. R., Tank, D. W. & Wieschaus, E. F. Proc. Natl Acad. Sci. USA 102, 18403–18407 (2005).

    Article  ADS  CAS  Google Scholar 

  14. Hamaratoglu, F., de Lachapelle, A. M., Pyrowolakis, G., Bergmann, S. & Affolter, M. PLoS Biol. 9, e1001182 (2011).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Naama Barkai and Ben-Zion Shilo are in the Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.,

    Naama Barkai & Ben-Zion Shilo

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  1. Naama Barkai
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  2. Ben-Zion Shilo
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Correspondence to Naama Barkai.

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Barkai, N., Shilo, BZ. Segmentation within scale. Nature 493, 32–33 (2013). https://doi.org/10.1038/nature11849

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