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Organic chemistry

Reactions at the end of a tether

A remarkable reaction that reverses the chemical behaviour of molecules known as 1,3-diketones allows a new strategy that could be used to prepare a range of potentially useful, naturally occurring compounds. See Letter p.86

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Figure 1: Allylation reactions of aldehydes and 1,3-diketones.

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Correspondence to Varinder K. Aggarwal.

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Roesner, S., Aggarwal, V. Reactions at the end of a tether. Nature 487, 48–49 (2012). https://doi.org/10.1038/nature11381

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