Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Boström et al. reply

Abstract

Replying to J. A. Timmons, K. Baar, P. K. Davidsen & P. J. Atherton Nature 488, 10.1038/nature11364 (2012)

This is a preview of subscription content

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Timmons, J. A., Baar, K., Davidsen, P. K. & Atherton, P. J. Is Irisin a human exercise gene? Nature 488, http://dx.doi.org/10.1038/nature11364 (2012)

  2. Boström, P. et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481, 463–468 (2012)

    ADS  Article  Google Scholar 

  3. Perry, C. G. R. et al. Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle. J. Physiol. 588, 4795–4810 (2010)

    CAS  Article  Google Scholar 

  4. Ristow, M. et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc. Natl Acad. Sci. USA 106, 8665–8670 (2009)

    ADS  CAS  Article  Google Scholar 

  5. Vissing, K. et al. Effect of sex differences on human MEF2 regulation during endurance exercise. Am. J. Physiol. Endocrinol. Metab. 294, E405–E415 (2008)

    Article  Google Scholar 

  6. Little, J. P., Safdar, A., Bishop, D., Tarnopolsky, M. A. & Gibala, M. J. An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle. Am. J. Physiol. Int. Comp. Physiol. 300, R1303–R1310 (2011)

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bruce M. Spiegelman.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Boström, P., Wu, J., Jedrychowski, M. et al. Boström et al. reply. Nature 488, E10–E11 (2012). https://doi.org/10.1038/nature11365

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature11365

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing