Table 1: Landscape of somatic alterations in primary human prostate cancers

From: The genomic complexity of primary human prostate cancer

 Tumour
 PR-0508PR-0581*PR-1701*PR-1783PR-2832*PR-3027PR-3043
Tumour bases sequenced97.8 × 10993.9 × 109110 × 10990.9 × 109106 × 10993.6 × 10994.9 × 109
Normal bases sequenced96.7 × 10957.8 × 109108 × 10992.3 × 109103 × 10987.8 × 10996.6 × 109
Tumour haploid coverage31.830.535.829.534.430.430.8
Normal haploid coverage31.418.834.930.033.428.531.4
Callable fraction0.840.830.870.820.840.840.85
Estimated tumour purity0.730.600.490.750.590.740.68
All point mutations (high confidence)3,898 (1,447)3,829 (1,430)3,866 (1,936)4,503 (2,227)3,465 (1,831)5,865 (2,452)3,192 (1,713)
Non-silent coding mutations (high confidence)16 (5)20 (3)24 (9)32 (20)13 (7)43 (16)14 (10)
Mutation rate per Mb0.70.70.81.00.81.20.7
Rearrangements53679021313315643
  1. *Harbours TMPRSS2–ERG gene fusion
  2. †Estimated from SNP array-derived allele specific copy number levels using the ABSOLUTE algorithm (Supplementary Methods).