Climate change and the global malaria recession

Abstract

The current and potential future impact of climate change on malaria is of major public health interest1,2. The proposed effects of rising global temperatures on the future spread and intensification of the disease3,4,5, and on existing malaria morbidity and mortality rates3, substantively influence global health policy6,7. The contemporary spatial limits of Plasmodium falciparum malaria and its endemicity within this range8, when compared with comparable historical maps, offer unique insights into the changing global epidemiology of malaria over the last century. It has long been known that the range of malaria has contracted through a century of economic development and disease control9. Here, for the first time, we quantify this contraction and the global decreases in malaria endemicity since approximately 1900. We compare the magnitude of these changes to the size of effects on malaria endemicity proposed under future climate scenarios and associated with widely used public health interventions. Our findings have two key and often ignored implications with respect to climate change and malaria. First, widespread claims that rising mean temperatures have already led to increases in worldwide malaria morbidity and mortality are largely at odds with observed decreasing global trends in both its endemicity and geographic extent. Second, the proposed future effects of rising temperatures on endemicity are at least one order of magnitude smaller than changes observed since about 1900 and up to two orders of magnitude smaller than those that can be achieved by the effective scale-up of key control measures. Predictions of an intensification of malaria in a warmer world, based on extrapolated empirical relationships or biological mechanisms, must be set against a context of a century of warming that has seen marked global declines in the disease and a substantial weakening of the global correlation between malaria endemicity and climate.

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Figure 1: Changing global malaria endemicity since 1900.

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Acknowledgements

We thank A. Bibby, H. C. J. Godfray, G. D. Shanks and G. R. W. Wint for comments on the manuscript. S.I.H. is funded by a Senior Research Fellowship from the Wellcome Trust (#079091) that also supports P.W.G. and previously A.J.T. R.W.S. is funded by a Principal Research Fellowship from the Wellcome Trust (#079080) that also supports A.P.P. D.L.S. and A.J.T. are supported by a grant from the Bill and Melinda Gates Foundation (#49446). D.L.S. and S.I.H. also acknowledge funding support from the RAPIDD program of the Science & Technology Directorate, Department of Homeland Security, and the Fogarty International Center, National Institutes of Health. This work forms part of the output of the Malaria Atlas Project (MAP, http://www.map.ox.ac.uk), principally funded by the Wellcome Trust, UK.

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S.I.H. conceived the research. P.W.G. and S.I.H. drafted the manuscript. P.W.G. led, and A.P.P., D.L.S., A.J.T. and R.W.S. contributed to, the analyses. All authors discussed the results and contributed to the revision of the final manuscript.

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Correspondence to Peter W. Gething or Simon I. Hay.

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Supplementary Information

This file contains Supplementary Information on (A) the weakening geographical relationship between climate and malaria endemicity 1900-2007 and (B) estimating changing endemicity in terns of PfR0 effect size, Supplementary References, Supplementary Figures S1-S2 with legends and Supplementary Tables S1-S3. (PDF 644 kb)

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Gething, P., Smith, D., Patil, A. et al. Climate change and the global malaria recession. Nature 465, 342–345 (2010). https://doi.org/10.1038/nature09098

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