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FCA does not bind abscisic acid

Nature volume 456, pages E5–E6 (2008)Cite this article

Abstract

Arising from: Fawzi A. Razem, Ashraf El-Kereamy, Suzanne R. Abrams & Robert D. Hill Nature 439, 290–294 (2006)10.1038/nature04373

The RNA-binding protein FCA promotes flowering in Arabidopsis1. Razem et al.2 reported that FCA is also a receptor for the phytohormone abscisic acid (ABA). However, we find that FCA does not bind ABA, suggesting that the quality of the proteins assayed and the sensitivity of the ABA-binding assay have led Razem et al. to erroneous conclusions. Because similar assays have been used to characterize other ABA receptors3,4, our results indicate that the ABA-binding properties of these proteins should be carefully re-evaluated and that alternative ABA receptors are likely to be discovered.

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Figure 1: ABA does not inhibit the FCA–FY interaction.
Figure 2: FCA does not bind ABA.

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Authors and Affiliations

  1. Biochemistry Department, University of Otago, Dunedin 9054, New Zealand

    Joanna M. Risk, Richard C. Macknight & Catherine L. Day

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  1. Joanna M. Risk
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  2. Richard C. Macknight
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  3. Catherine L. Day
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Risk, J., Macknight, R. & Day, C. FCA does not bind abscisic acid. Nature 456, E5–E6 (2008). https://doi.org/10.1038/nature07646

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