Brief Communications Arising | Published:

FCA does not bind abscisic acid

Nature volume 456, pages E5E6 (11 December 2008) | Download Citation



Arising from: Fawzi A. Razem, Ashraf El-Kereamy, Suzanne R. Abrams & Robert D. Hill Nature 439, 290–294 (2006)10.1038/nature04373

The RNA-binding protein FCA promotes flowering in Arabidopsis1. Razem et al.2 reported that FCA is also a receptor for the phytohormone abscisic acid (ABA). However, we find that FCA does not bind ABA, suggesting that the quality of the proteins assayed and the sensitivity of the ABA-binding assay have led Razem et al. to erroneous conclusions. Because similar assays have been used to characterize other ABA receptors3,4, our results indicate that the ABA-binding properties of these proteins should be carefully re-evaluated and that alternative ABA receptors are likely to be discovered.

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  1. *Biochemistry Department, University of Otago, Dunedin 9054, New Zealand.

    • Joanna M. Risk
    • , Richard C. Macknight
    •  & Catherine L. Day


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