Progress Article | Published:

Applying mouse complex-trait resources to behavioural genetics

Nature volume 456, pages 724727 (11 December 2008) | Download Citation

Abstract

Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will enable the behavioural function of all genes to be tested and the networks of genes, messenger RNAs and proteins involved in a particular behaviour to be identified. Using these resources, scientists will be able to analyse mouse behaviour at an unprecedented level of detail. Interpreting the new data, however, will require a shift in focus from gene-based approaches to network-based approaches.

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Acknowledgements

We thank the Wellcome Trust for support and are grateful to S.McCormick for comments on the manuscript.

Author information

Affiliations

  1. Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

    • Jonathan Flint
    •  & Richard Mott

Authors

  1. Search for Jonathan Flint in:

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Competing interests

The authors declare no competing financial interests.

Reprints and permissions information is available at http://www.nature.com/reprints.

Correspondence should be addressed to J.F. (jf@well.ox.ac.uk).

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DOI

https://doi.org/10.1038/nature07630

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