Progress Article | Published:

Next-generation genetics in plants

Nature volume 456, pages 720723 (11 December 2008) | Download Citation



Natural variation presents one of the fundamental challenges of modern biology. Soon, the genome sequences of thousands of individuals will be known for each of several species. But how does the genotypic variation that will be observed among these individuals translate into phenotypic variation? Plants are in many ways ideal for addressing this question, and resources that are unmatched, except in humans, have now been developed.

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Studies of natural genetic variation are supported by the National Science Foundation and the National Institutes of Health (M.N.), and by the German Research Foundation, the German Federal Ministry of Education and Research, the European Union's Sixth Framework Programme, the Human Frontier Science Program and the Max Planck Society (D.W.).

Author information


  1. Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA.

    • Magnus Nordborg
  2. Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

    • Detlef Weigel


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