Table 1 Single nucleotide variation in 454 reads

From: The complete genome of an individual by massively parallel DNA sequencing

Subject Filter* Total variation Known† Novel
Watson Raw 14,829,087 3,283,273 11,545,814
  1 4,427,488 2,815,322 1,612,166
  2 3,971,513 2,752,991 1,218,522
  3 3,322,093 2,715,296 606,797
Venter‡ 4 3,470,669 2,822,902 647,767
  1. *Filters: raw, all base substitution from cross_match alignments; 1, Sv > 28 (see Methods); 2, filter 1 plus ratio of variant to total coverage >0.2; 3, filter 2 plus eliminate SNPs close to homopolymer runs >5 bp; 4, (Venter) Phred (ref. 20) Q > 15, ratio of variant to total coverage >0.2.
  2. †Variants found in build 126 of dbSNP (http://www.ncbi.nlm.nih.gov/SNP/).
  3. ‡SNPs found in genome of Venter: see ref. 2 and supplementary material therein.