Neural mechanisms mediating optimism bias

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Abstract

Humans expect positive events in the future even when there is no evidence to support such expectations. For example, people expect to live longer and be healthier than average1, they underestimate their likelihood of getting a divorce1, and overestimate their prospects for success on the job market2. We examined how the brain generates this pervasive optimism bias. Here we report that this tendency was related specifically to enhanced activation in the amygdala and in the rostral anterior cingulate cortex when imagining positive future events relative to negative ones, suggesting a key role for areas involved in monitoring emotional salience in mediating the optimism bias. These are the same regions that show irregularities in depression3, which has been related to pessimism4. Across individuals, activity in the rostral anterior cingulate cortex was correlated with trait optimism. The current study highlights how the brain may generate the tendency to engage in the projection of positive future events, suggesting that the effective integration and regulation of emotional and autobiographical information supports the projection of positive future events in healthy individuals, and is related to optimism.

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Figure 1: Optimism related to expected time of event and sense of pre-experiencing future events.
Figure 2: Activity in the amygdala and rACC and its relation to optimism.
Figure 3: Brain activity during past and future trials.

References

  1. 1

    Weinstein, N. D. Unrealistic optimism about future life events. J. Pers. Soc. Psychol. 39, 806–820 (1980)

  2. 2

    Hoch, S. Conterfactual reasoning and accuracy in predicting personal events. J. Exp. Psychol. 11, 719–731 (1984)

  3. 3

    Drevets, W. C. et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386, 824–827 (1997)

  4. 4

    Strunk, D. R., Lopez, H. & DeRubeis, R. J. Depressive symptoms are associated with unrealistic negative predictions of future life events. Behav. Res. Ther. 44, 861–882 (2006)

  5. 5

    Lovallo, D. & Kahneman, D. Delusions of success: how optimism undermines executives’ decisions. Harv. Bus. Rev. 56, 56–63 (2003)

  6. 6

    Taylor, S. E. & Brown, J. D. Illusion and well-being: a social psychological perspective on mental health. Psychol. Bull. 103, 193–210 (1988)

  7. 7

    Scheier, M. F. & Carver, C. S. Dispositional optimism and physical well-being: the influence of generalized outcome expectancies on health. J. Pers. 55, 169–210 (1987)

  8. 8

    Addis, D. R., Wong, A. T. & Schacter, D. L. Remembering the past and imagining the future: common and distinct neural substrates during event construction and elaboration. Neuropsychologia 45, 1363–1377 (2007)

  9. 9

    Tulving, E. in The Missing Link in Cognition (eds Terrace, H. S. & Metcalfe, J.) 3–56 (Oxford Univ. Press, New York, 2005)

  10. 10

    Okuda, J. et al. Thinking of the past and past: the roles of the frontal pole and the medial temporal lobe. Neuroimage 19, 1369–1380 (2003)

  11. 11

    Hassabis, D., Kumaran, D., Vann, S. D. & Marguire, E. A. Patients with hippocampal amnesia cannot imagine new experiences. Proc. Natl Acad. Sci. USA 104, 1726–1731 (2007)

  12. 12

    D’Argembeau, A. & Van der Linden, M. Influence of affective meaning on memory for contextual information. Emotion 4, 173–188 (2004)

  13. 13

    Scheier, M. F., Carver, C. S. & Bridges, M. W. Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem): a reevaluation of the Life Orientation Test. J. Pers. Soc. Psychol. 67, 1063–1078 (1994)

  14. 14

    Sharot, T., Martorella, E. A., Delgado, M. R. & Phelps, E. A. How personal experience modulates the neural circuitry of memories of September 11. Proc. Natl Acad. Sci. USA 104, 389–394 (2007)

  15. 15

    Phelps, E. A. Emotion and cognition: insights from studies of the human amygdala. Annu. Rev. Psychol. 57, 27–53 (2006)

  16. 16

    Vogt, B. A. & Pandya, D. N. Cingulate cortex of the rhesus monkey: II. cortical afferents. J. Comp. Neurol. 262, 271–289 (1987)

  17. 17

    Moran, J. M., Macrae, C. N., Heatherton, T. F., Wyland, C. L. & Kelley, W. M. Neuroanatomical evidence for distinct cognitive and affective components of self. J. Cogn. Neurosci. 18, 1586–1594 (2006)

  18. 18

    Johnson, S. C., Baxter, L. C., Wilder, L. S., Pipe, J. G., Heiserman, J. E. & Prigatano, G. P. Neural correlates of self-reflection. Brain 125, 1808–1814 (2002)

  19. 19

    Paulus, M. P. & Frank, L. R. Ventromedial prefrontal cortex activation is critical for preference judgments. Neuroreport 14, 1311–1315 (2003)

  20. 20

    Winston, J. S., Strange, B. A., O’Doherty, J. & Dolan, R. J. Automatic and intentional brain responses during evaluation of trustworthiness of faces. Nature Neurosci. 5, 277–283 (2002)

  21. 21

    Bush, G., Luu, P. & Posner, M. I. Cognitive and emotional influences in anterior cingulated cortex. Trends Cogn. Sci. 14, 215–222 (2000)

  22. 22

    Cunningham, W. A., Raye, C. L. & Johnson, M. K. Neural correlates of evaluation associated with promotion and prevention regulatory focus. Cogn. Affect. Behav. Neurosci. 5, 202–211 (2005)

  23. 23

    Phelps, E. A., Delgado, M. R., Nearing, K. I. & LeDoux, J. E. Extinction learning in humans: role of the amygdala and vmPFC. Neuron 43, 897–905 (2004)

  24. 24

    Simpson, J. R., Snyder, A. Z., Gusnard, D. A. & Raichle, M. E. Emotion-induced changes in human medial prefrontal cortex: I. during cognitive task performance. Proc. Natl Acad. Sci. USA 98, 688–693 (2001)

  25. 25

    Williams, J. M., Ellis, N. C., Tyers, C., Healy, H., Rose, G. & MacLeod, A. K. The specificity of autobiographical memory and imageability of the future. Mem. Cognit. 24, 116–125 (1996)

  26. 26

    Roebroeck, A., Formisano, E. & Goebel, R. Mapping directed influence over the brain using Granger causality and fMRI. Neuroimage 25, 230–242 (2005)

  27. 27

    Pruessner, J. C. et al. Volumetry of hippocampus and amygdala with high-resolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories. Cereb. Cortex 10, 433–442 (2000)

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Acknowledgements

This study was supported by the NIMH (E.A.P.), the Seaver Foundation (grant to NYU’s Center for Brain Imaging), and a Margaret and Herman Sokol Postdoctoral Fellowship (T.S.). We thank S. H. Mulhern, D. C. Johnson and J. K. Szary for help in data analysis, and D. Schiller, J. H. McDermott and Y. Trope for discussion.

Author Contributions T.S. designed the study. T.S. and E.A.P. interpreted the data and wrote the paper. T.S. and A.M.R. developed stimuli, gathered behavioural pilot data, and conducted behavioural data analysis. T.S. gathered fMRI data. T.S. conducted neuroimaging analyses with the help of A.M.R. and C.M.R., and with advice of E.A.P. Whole-brain exploratory analysis was conducted by C.M.R.

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Correspondence to Elizabeth A. Phelps.

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The authors declare no competing financial interests.

Supplementary information

Supplementary Information

The file contains Supplementary Table 1, Supplementary Figure 1 and Legend, Supplementary Data, Supplementary Discussion, Supplementary Methods and additional references. (PDF 173 kb)

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Sharot, T., Riccardi, A., Raio, C. et al. Neural mechanisms mediating optimism bias. Nature 450, 102–105 (2007) doi:10.1038/nature06280

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