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Chemical Biology

Ignore the nonsense

A small molecule forces the protein-translation machinery to overlook the signals that would otherwise result in its premature termination. Genuine stop signs are, however, read and obeyed.

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Figure 1: Possible mechanisms of PTC124-enhanced translation.

Notes

  1. This article and the paper concerned1 were published online on 22 April 2007.

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Schmitz, A., Famulok, M. Ignore the nonsense. Nature 447, 42–43 (2007). https://doi.org/10.1038/nature05715

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