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Human genetics

Variants in common diseases

Nature volume 445, pages 828–829 (2007)Cite this article

Most common diseases arise from interaction between multiple genetic variations and factors such as diet. Studies of such diseases that exploit the rich data on variation in the human genome are just beginning.

The results of the first genome-wide-association (GWA) surveys of common diseases are trickling out. This trickle will soon be a flood of data, much anticipated but challenging to interpret. These initial studies will calibrate our expectations for future investigations, and help to establish the principles for how they are best reported.

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Notes

  1. This article and the paper concerned1 were published online on 11 February 2007.

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Authors and Affiliations

  1. Nelson B. Freimer is in the UCLA Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, 695 Charles Young Drive South, Los Angeles, California 90095-1761, USA. nfreimer@mednet.ucla.edu,

    Nelson B. Freimer

  2. Chiara Sabatti is in the UCLA Departments of Human Genetics and Statistics, 695 Charles Young Drive South, Los Angeles, California 90095-7088, USA. csabatti@mednet.ucla.edu,

    Chiara Sabatti

Authors
  1. Nelson B. Freimer
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  2. Chiara Sabatti
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Freimer, N., Sabatti, C. Variants in common diseases. Nature 445, 828–829 (2007). https://doi.org/10.1038/nature05568

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