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Reducing the burden of sexually transmitted infections in resource-limited settings: the role of improved diagnostics

Nature volume 444, pages 5972 (23 November 2006) | Download Citation

There is a great need for improved diagnosis of curable bacterial sexually transmitted infections among women in developing countries. We found that wider access to new diagnostic tests has a greater overall impact on health outcomes than improvements in test sensitivity or specificity.

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The authors thank B. Schackman (Weill Medical College of Cornell University, New York, USA) and G. Garnett (Imperial College London, UK) for helpful comments on earlier drafts. In addition, we thank F. Terris-Prestholt (London School of Hygiene and Tropical Medicine, UK) and P. Mwaba (University of Zambia, School of Medicine, Lusaka Zambia) for contributions to the analysis and K. Leuschner (RAND Corporation, Santa Monica, California, USA) for assistance in drafting the manuscript.

Author information


  1. RAND Corporation, 1776 Main Street, PO Box 2138, Santa Monica, California 90407-2138, USA

    • Julia E. Aledort
    • , Maria E. Rafael
    • , Federico Girosi
    •  & Molly V. Shea
  2. University of Manitoba, 709-99 Wellington Crescent, Winnipeg, Manitoba R3M 0A2, Canada

    • Allan Ronald
  3. Health Policy Unit, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK

    • Peter Vickerman
  4. Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue B1, New York, New York 10032, USA

    • Sylvie M. Le Blancq
  5. Rush University Medical Center, 1735 West Harrison Street, Chicago, Illinois 60612, USA

    • Alan Landay
  6. Center for AIDS and STDs, Harborview Medical Center, University of Washington, PO Box 359931, 325 9th Avenue, Seattle, Washington 98104, USA

    • King Holmes
  7. Bill & Melinda Gates Foundation, PO Box 23350, Seattle, Washington 98102, USA

    • Renee Ridzon
    •  & Nicholas Hellmann
  8. World Health Organization, 20 Avenue Appia, Geneva CH-12118, Switzerland

    • Rosanna W. Peeling


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Correspondence to Julia E. Aledort.

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