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Reducing the global burden of tuberculosis: the contribution of improved diagnostics

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We estimated the impact of hypothetical new diagnostic tests for tuberculosis (TB) in patients with persistent cough in developing countries. We found that a variety of new tests could help better identify TB cases and target treatment, thereby reducing the burden of disease.

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Acknowledgements

The authors thank M. Weinstein (Harvard School of Public Health, Massachusetts, USA) and M. Zignol (World Health Organization, Geneva, Switzerland) for their comments on an earlier draft of this paper.

Author information

Affiliations

  1. RAND Corporation, 1776 Main Street, PO Box 2138, Santa Monica, California 90407-2138, USA

    • Emmett Keeler
    • , Julia E. Aledort
    • , Lee Hillborne
    • , Maria E. Rafael
    •  & Federico Girosi
  2. Foundation for Innovative New Diagnostics, 71 Avenue Louis Casai, PO Box 93, 1216 Cointrin, Switzerland

    • Mark D. Perkins
  3. Bill & Melinda Gates Foundation, PO Box 23350, Seattle, Washington 98102, USA

    • Peter Small
  4. United States Agency for International Development, 1300 Pennsylvania Avenue North West, Washington DC 20523, USA

    • Christy Hanson
  5. Infectious Disease Research Institute, 1124 Columbia Street, Seattle, Washington 98104, USA

    • Steven Reed
  6. World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland

    • Jane Cunningham
    •  & Christopher Dye

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Corresponding author

Correspondence to Emmett Keeler.

This article has not been written or reviewed by the Nature editorial team and Nature takes no responsibility for the accuracy or otherwise of the information provided.

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