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Grapes versus gluttony

A compound found in red grapes called resveratrol improves the health and lifespan of mice on a high-calorie diet. This is potentially good news for overweight humans. Does it bode well for the rest of us too?

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  1. *This article and the paper concerned1 were published online on 1 November 2006.

References

  1. Baur, J. A. et al. Nature 444, 337–342 (2006).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  2. Soleas, G. J., Diamandis, E. P. & Goldberg, D. M. Clin. Biochem. 30, 91–113 (1997).

    Article  CAS  PubMed  Google Scholar 

  3. Howitz, K. T. et al. Nature 425, 191–196 (2003).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Longo, V. D. & Kennedy, B. K. Cell 126, 257–268 (2006).

    Article  CAS  PubMed  Google Scholar 

  5. Kaeberlein, M. et al. J. Biol. Chem. 280, 17038–17045 (2005).

    Article  CAS  PubMed  Google Scholar 

  6. Wood, J. G. et al. Nature 430, 686–689 (2004).

    Article  ADS  CAS  PubMed  Google Scholar 

  7. Valenzano, D. R. et al. Curr. Biol. 16, 296–300 (2006).

    Article  CAS  PubMed  Google Scholar 

  8. Baur, J. A. & Sinclair, D. A. Nature Rev. Drug Discov. 5, 493–506 (2006).

    Article  CAS  Google Scholar 

  9. Borra, M. T., Smith, B. C. & Denu, J. M. J. Biol. Chem. 280, 17187–17195 (2005).

    Article  CAS  PubMed  Google Scholar 

  10. Zang, M. et al. Diabetes 55, 2180–2191 (2006).

    Article  CAS  PubMed  Google Scholar 

  11. www.nia.nih.gov/ResearchInformation/ScientificResources/InterventionsTestingProgram.htm

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Kaeberlein, M., Rabinovitch, P. Grapes versus gluttony. Nature 444, 280–281 (2006). https://doi.org/10.1038/nature05308

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