A compound found in red grapes called resveratrol improves the health and lifespan of mice on a high-calorie diet. This is potentially good news for overweight humans. Does it bode well for the rest of us too?
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Notes
*This article and the paper concerned1 were published online on 1 November 2006.
References
Baur, J. A. et al. Nature 444, 337–342 (2006).
Soleas, G. J., Diamandis, E. P. & Goldberg, D. M. Clin. Biochem. 30, 91–113 (1997).
Howitz, K. T. et al. Nature 425, 191–196 (2003).
Longo, V. D. & Kennedy, B. K. Cell 126, 257–268 (2006).
Kaeberlein, M. et al. J. Biol. Chem. 280, 17038–17045 (2005).
Wood, J. G. et al. Nature 430, 686–689 (2004).
Valenzano, D. R. et al. Curr. Biol. 16, 296–300 (2006).
Baur, J. A. & Sinclair, D. A. Nature Rev. Drug Discov. 5, 493–506 (2006).
Borra, M. T., Smith, B. C. & Denu, J. M. J. Biol. Chem. 280, 17187–17195 (2005).
Zang, M. et al. Diabetes 55, 2180–2191 (2006).
www.nia.nih.gov/ResearchInformation/ScientificResources/InterventionsTestingProgram.htm
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kaeberlein, M., Rabinovitch, P. Grapes versus gluttony. Nature 444, 280–281 (2006). https://doi.org/10.1038/nature05308
Issue Date:
DOI: https://doi.org/10.1038/nature05308
This article is cited by
-
Biocatalysis and biotransformation of resveratrol in microorganisms
Biotechnology Letters (2015)
-
Resveratrol lacks antifungal activity against Candida albicans
World Journal of Microbiology and Biotechnology (2012)
-
Enhanced extracellular production of trans-resveratrol in Vitis vinifera suspension cultured cells by using cyclodextrins and methyljasmonate
Plant Cell Reports (2012)
-
A votre santé: now in pill form?
Nature (2006)