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Nitrate at the ion exchange

The distinction between CLC ion channels and ion exchangers has become blurred. The physiological role of CLC exchangers has been a mystery, but one function is evidently to concentrate nitrate in plant vacuoles.

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Figure 1: Nitrate accumulation in plant vacuoles mediated by the proton–nitrate (H+–NO3) exchanger AtCLCa.


  1. This article and the paper concerned4 were published online on 26 July 2006.


  1. Accardi, A. & Miller, C. Nature 427, 803–807 (2004).

    Article  ADS  CAS  Google Scholar 

  2. Picollo, A. & Push, M. Nature 436, 420–423 (2005).

    Article  ADS  CAS  Google Scholar 

  3. Scheel, O., Zdebik, A. A., Lourdel, S. & Jentsch, T. J. Nature 436, 424–427 (2005).

    Article  ADS  CAS  Google Scholar 

  4. De Angeli, A. et al. Nature 442, 939–942 (2006).

    Article  ADS  CAS  Google Scholar 

  5. Jentsch, T. J. et al. Nature 348, 510–514 (1990).

    Article  ADS  CAS  Google Scholar 

  6. Jentsch, T. J., Poet, M., Fuhrmann, J. C. & Zdebik, A. A. Annu. Rev. Physiol. 67, 779–807 (2005).

    Article  CAS  Google Scholar 

  7. Geelen, D. et al. Plant J. 21, 259–267 (2000).

    Article  CAS  Google Scholar 

  8. Cookson, S. J., Williams, L. E. & Miller, A. J. Plant Physiol. 138, 1097–1105 (2005).

    Article  CAS  Google Scholar 

  9. Dutzler, R. et al. Nature 415, 287–294 (2002).

    Article  ADS  CAS  Google Scholar 

  10. Miller, C. Nature 440, 484–489 (2006).

    Article  ADS  CAS  Google Scholar 

  11. Miller, C. Phil. Trans. R. Soc. Lond. B 299, 401–411 (1982).

    Article  ADS  CAS  Google Scholar 

  12. Accardi, A. et al. J. Gen. Physiol. 126, 563–570 (2005).

    Article  CAS  Google Scholar 

  13. Teardo, E. et al. FEBS Lett. 579, 4991–4996 (2005).

    Article  CAS  Google Scholar 

  14. Sussman, M. R. Annu. Rev. Plant Physiol. Plant Mol. Biol. 45, 211–234 (1994).

    Article  CAS  Google Scholar 

  15. Schroeder, J. I. & Hagiwara, S. Nature 338, 427–430 (1989).

    Article  ADS  Google Scholar 

  16. Hedrich, R., Busch, H. & Raschke, K. EMBO J. 9, 3889–3892 (1990).

    Article  CAS  Google Scholar 

  17. Linder, B. & Raschke, K. FEBS Lett. 313, 27–30 (1992).

    Article  CAS  Google Scholar 

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Schroeder, J. Nitrate at the ion exchange. Nature 442, 877–878 (2006).

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