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Stem cells for the treatment of neurological disorders

Naturevolume 441pages10941096 (2006) | Download Citation

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Abstract

Many common neurological disorders, such as Parkinson's disease, stroke and multiple sclerosis, are caused by a loss of neurons and glial cells. In recent years, neurons and glia have been generated successfully from stem cells in culture, fuelling efforts to develop stem-cell-based transplantation therapies for human patients. More recently, efforts have been extended to stimulating the formation and preventing the death of neurons and glial cells produced by endogenous stem cells within the adult central nervous system. The next step is to translate these exciting advances from the laboratory into clinically useful therapies.

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Author information

Affiliations

  1. Laboratory of Neurogenesis and Cell Therapy, Section of Restorative Neurology, Wallenberg Neuroscience Center, Lund, SE-221 84, Sweden

    • Olle Lindvall
  2. Laboratory of Neural Stem Cell Biology, Section of Restorative Neurology, Stem Cell Institute, University Hospital, SE-221 84, Lund, Sweden

    • Zaal Kokaia
  3. Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund, Sweden

    • Olle Lindvall
    •  & Zaal Kokaia

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The authors declare no competing financial interests.

Corresponding author

Correspondence to Olle Lindvall.

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https://doi.org/10.1038/nature04960

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