a, Conserved synteny between loci. Grey lines indicate predicted orthologues. Red genes indicate orthologues from the left flank (as drawn) of the A. nidulans alpha locus with the left flanks of the A. fumigatus and A. oryzae loci. Cyan genes indicate orthologues with the right flank of the A. nidulans HMG locus. The bottom panel shows the region near mating-type genes. Genes labelled and outlined in black are associated with MAT loci in other fungi. Only partial accession numbers (suffixes) are shown in the figure. For full accession numbers, the numbers shown in the panel should replace the asterisks in the following examples: A. nidulans (AN****.1); A. fumigatus (59.m0****); A. oryzae (AO0703270000**). b, Model of structural evolution of the MAT loci. Braces represent multiple haplotypes at the same genomic locus. The experimental identification of other isolates (indicated by an asterisk) was reported in another study15. The light blue arrow indicates a 360-bp HMG gene fragment. AF, A. fumigatus; AN, A. nidulans; AO, A. oryzae.