Nature 423, 91–96 (2003).
In this Letter, it is shown using transgene insertion mouse mutants that the Makorin1-p1 pseudogene regulates the expression of its related coding gene. An example has been drawn to our attention of another transcribed pseudogene that regulates the expression of its related coding gene, but by a different mechanism, in the mollusc Lymnaea stagnalis1.
References
Korneev, S. A., Park, J.-H. & O'Shea, M. Neuronal expression of neural nitric oxide synthase (nNOS) protein is suppressed by an antisense RNA transcribed from an NOS pseudogene. J. Neurosci. 19, 7711–7720 (1999)
Rights and permissions
About this article
Cite this article
Hirotsune, S., Yoshida, N., Chen, A. et al. Addendum: An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene. Nature 426, 100 (2003). https://doi.org/10.1038/nature02094
Issue Date:
DOI: https://doi.org/10.1038/nature02094
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
