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From genomics to proteomics


Proteomics is the study of the function of all expressed proteins. Tremendous progress has been made in the past few years in generating large-scale data sets for protein–protein interactions, organelle composition, protein activity patterns and protein profiles in cancer patients. But further technological improvements, organization of international proteomics projects and open access to results are needed for proteomics to fulfil its potential.

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Figure 1: Platforms for proteomics and functional genomics.
Figure 2: Visualization of combined, large-scale interaction data sets in yeast.


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We thank B.-J. Breitkreutz for preparing Fig. 2, D. Figeys and members of the Center for Experimental BioInformatics (CEBI) for critical reading of the manuscript. CEBI is supported by a grant from the Danish Natural Research Foundation.

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Tyers, M., Mann, M. From genomics to proteomics. Nature 422, 193–197 (2003).

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