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Unravelling the signal-transduction network in B lymphocytes

Nature volume 420, pages 708–710 (2002)Cite this article

Abstract

The Alliance for Cellular Signaling has chosen the mouse B lymphocyte as a model system to understand basic principles that govern cellular signalling. Progress to that end has focused initially on establishing a reproducible experimental cell system and characterizing essential signalling responses. Although unravelling this complex network will take years, findings revealed in the interim will prove immensely useful to the scientific community at large.

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Authors and Affiliations

  1. Department of Cellular and Molecular Pharmacology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, 94143, California, USA

    Gilberto R. Sambrano & Henry Bourne

  2. Department of Molecular Pharmacology, Stanford University School of Medicine, 975 California Avenue, Palo Alto, 94305, California, USA

    Grischa Chandy, Nancy O'Rourke & Mary Verghese

  3. Biology Division, 147-75, California Institute of Technology, Pasadena, 91125, California, USA

    Sangdun Choi

  4. Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, 75390, Texas, USA

    Dianne Decamp, Robert Hsueh, Keng-Mean Lin & Hongjun Shu

  5. San Diego Supercomputer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, 92093, California, USA

    Dennis Mock & Bob Sinkovits

  6. Department of Rheumatology, San Francisco Veterans Administration Medical Center, 4150 Clement Street, San Francisco, 94121, California, USA

    Tamara Roach

Authors
  1. Gilberto R. Sambrano
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  2. Grischa Chandy
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  3. Sangdun Choi
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  4. Dianne Decamp
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  5. Robert Hsueh
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  6. Keng-Mean Lin
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  7. Dennis Mock
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  13. Henry Bourne
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Correspondence to Gilberto R. Sambrano.

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Sambrano, G., Chandy, G., Choi, S. et al. Unravelling the signal-transduction network in B lymphocytes. Nature 420, 708–710 (2002). https://doi.org/10.1038/nature01305

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