Starting to smoke pot in your teens can lead to cognitive decline not seen in those who start as adults.
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References
Meier, M. H. et al. Proc. Natl Acad. Sci. http://dx.doi.org/10.1073/pnas.1206820109 (2012).
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Phillips, L. Drop in IQ linked to heavy teenage cannabis use. Nature (2012). https://doi.org/10.1038/nature.2012.11278
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DOI: https://doi.org/10.1038/nature.2012.11278