Table 1: Clusters showing differences between MDD and controls that met our criteria for robustness

From: Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

Peak MNI coordinateZPVoxelsBrodmann areasRegions
MDD<Healthy controls
 −42, 8, −24.05<0.001325822, 38, 48Left insula, inferior frontal gyrus, temporal pole, superior temporal gyrus
 54, −8, −144.00<0.001191221, 22, 48Right superior temporal gyrus, insula, inferior frontal gyrus
 −2, 40, −183.40<0.00190811Left gyrus rectus, left medial orbitofrontal cortex, anterior cingulate cortex
 0, 4, 423.34<0.00172923, 24Left middle cingulate cortex
 −10, 16, 63.53<0.00132025Left caudate nucleus
 44, 48, −83.12<0.00128246, 47Right middle frontal gyrus, orbital part
 32, 42, 303.10<0.00114446Right middle frontal gyrus
 −28, −38, −42.880.00110437Left hippocampus, parahippocampal gyrus
 −40, −54, 463.21<0.0019340Left inferior lobule
 44, −24, −242.780.0019220Right fusiform gyrus
 4, 48, 222.800.0015332Right anterior cingulate cortex
 −20, −18, −182.730.0014135Left hippocampus, parahippocampal gyrus
 −4, 36, 402.670.0013632Left superior medial frontal gyrus
      
MDD>Healthy controls
 26, −90, 14−1.81~073117, 18Right superior occipital gyrus, cuneus, middle occipital gyrus
 −10, −96, 12−1.03<0.00173317, 18Left superior occipital gyrus
 44, −50, 26−1.33<0.00145739Right angular gyrus, middle temporal gyrus
 52, −4, 26−1.25<0.0011614Right postcentral gyrus
  1. Abbreviation: MDD, major depressive disorder.