Table 3: Results of genetic correlation using LD score regression

From: GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

Genetic correlation with other traits using LD score regression     
GroupPhenotypergs.e.zP-value
CognitionChildhood IQ0.890.127.411.24E13
 College degree0.660.079.981.88E23
 Years of education0.730.0416.831.48E63
NeuropsychiatricADHD−0.350.16−2.143.22E−02
 Alzheimer's0.130.111.172.41E01
 Anorexia0.020.100.248.08E01
 Anxiety−0.500.19−2.571.03E−02
 Autism0.280.083.436.00E04
 Bipolar0.000.080.069.52E01
 Major depression0.100.100.963.35E01
 Schizophrenia0.170.053.534.09E04
PersonalityExtraversion0.130.101.361.74E01
 Agreeableness1.241.241.003.17E01
 Conscietousness0.100.140.744.61E01
 Openness0.480.133.593.25E04
 Neuroticism0.180.121.491.35E01
SmokingAge of onset0.210.131.679.49E02
 Cigarettes per day0.030.110.277.85E01
 Ever smoker−0.240.08−3.072.13E−03
 Former smoker0.290.102.805.09E−03
Brain volumeAccumbens0.260.151.748.18E02
 Caudate0.080.100.794.30E01
 Hippocampus0.240.131.886.06E02
 Intracranial volume0.140.131.092.77E01
 Pallidum0.160.131.282.02E01
 Putamen0.130.091.441.50E01
 Thalamus0.130.121.072.83E01
Early growthBirth length0.200.092.133.33E−02
 Birth weight0.150.052.893.90E−03
 Infant head Circumference0.190.111.699.04E02
  1. Abbreviations: ADHD, attention-deficit/hyperactivity disorder; IQ, intelligence quotient; LD, linkage disequilibrium. Traits that are in bold font were nominally significant (P<0.05); traits that are italicized were significant after Bonferroni correction.