Carriage of the S′ allele serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) may influence brain morphology

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Decreased gray matter volume in healthy volunteers with short S′ allele vs long L′L′ homozygotes of serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531). The figure shows whole-brain analysis with a cluster with decreased volume in the right inferior frontal gyrus studied using high-resolution 3T MRI and FSL voxel-based morphometry. The image is displayed in axial, coronal and sagittal sections, with numerals referring to coordinates in Montreal Neurological Institute space. Images are shown in radiological format. Color scales used represent t-scores. For more info on this topic, please refer to the article by Selvaraj et al. on pages 472–473.

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Selvaraj, S., Godlewska, B., Norbury, R. et al. Carriage of the S′ allele serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) may influence brain morphology. Mol Psychiatry 16, 471 (2011) doi:10.1038/mp.2011.40

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