Figure 6

From: Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection

Figure 6

Increased IgG1 levels in group A β-hemolytic streptococcus (GABHS) donor sera. Immunoglobulin subclasses were assayed in serum samples from GABHS and phosphate-buffered saline (PBS) donor mice using multiplexed, bead-based immunoassay. Results indicate mean concentration (μg ml−1). Serum IgG1 levels were increased in GABHS donor mice as compared to PBS donors (Mann–Whitney U; *P<0.05). Height of box plot shows interquartile range; horizontal line, median; error bars, range; circles, outliers.