Figure 4

From: Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection

Figure 4

Olfactory discrimination deficits in group A β-hemolytic streptococcus (GABHS) donor mice. GABHS and phosphate-buffered saline (PBS) donor mice were habituated over four trials to a novel odor (acquisition/habituation trials). A second novel odor was presented in the fifth (discrimination) trial. Data are presented as the time spent investigating the novel odor normalized to time investigating the control odor (water). GABHS donor mice spent less time investigating the novel odor in the discrimination trial compared with control mice (Fisher's protected least-significant difference (PLSD); *P<0.05). Error bars indicate s.e.m.